ABOUT US

JEAN-YVES MASSON

 

My interest in DNA repair began during my PhD where I studied the function of base excision repair enzymes using budding yeast S. cerevisiae genetics. Since my Ph.D. was focused on base excision repair, I wanted to have a better knowledge of how the cell repairs double-strand breaks. I joined the laboratory of Dr. Steve West (Cancer Research UK) for four years to study DNA repair by homologous recombination using biochemical and cellular approaches.

 

Our current work, in my own laboratory at the Laval University Cancer Research Center, is divided between basic science studies of DNA repair and studies aimed at manipulating DNA repair pathways for therapeutic benefit. Basic science studies in the laboratory focus mainly on the characterization of the MRE11-RAD50-NBS1 complex, breast/ovarian PALB2 and BRCA2 proteins and Fanconi anemia enzymes in DNA double-strand break repair by homologous recombination. We are also currently developing synthetic lethal strategies, based on the function of some of these enzymes, to selectively kill ovarian and breast cancer cells using PARP inhibitors. 

 

TEAM 

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Yan Coulombe

Research assistant

yancoulombe@gmail.com

Marie-Christine Caron

Research assistant

marie_ccaron@hotmail.com

 

Isabelle Brodeur

Administrative  assistant 

(part time)

isabrodeur@hotmail.com

Daryl Ronato

PhD student (Jan 2017)

daryl.ronato11@gmail.com

Julia O'Sullivan (co-direction with Guy Poirier)

PhD student (Sept 2016)

julia.o-sullivan@ucdconnect.ie

Laura Sesma

PhD student (Jan 2017)

sesma.sanz.laura@gmail.com

 

Laure Guitton-Sert 

Postdoctoral fellow (Jan 2017)

guittonsert@gmail.com

Amélie Rodrigue

Research assistant

Amelie.Rodrigue@crchudequebec.ulaval.ca

 

Adèle Beyneton

PhD student

 (Sept 2019)

 

FORMER MEMBERS

Graduates of the lab (well done !)

Isabelle Banville, MSc, 2004.

Synthia Sauvageau, MSc, 2006. Tableau d'honneur de l'Université Laval. Now at GSK. 

Ugo Déry, PhD, 2007. Tableau d'honneur de l'Université Laval. Now Clinical Research Associate (PAREXEL)

Sandra Piquet, MSc 2009. Co-direction with Dr Martin Simard (co-directeur). 

Mickael Ploquin, MSc et PhD 2009. Tableau d'honneur de l'Université Laval. Now at NEB. 

Ali Bransi, MSc 2009. Tableau d'honneur de l'Université Laval. 

Céline Roques, PhD 2009. 

Anne-Marie Dion-Côté, MSc 2010. Tableau d'honneur de l'Université Laval. Now PDF at Cornell. 

Amélie Rodrigue, MSc et PhD 2011. Tableau d'honneur de l'Université Laval. Now a research assistant in our lab. 

Anurhada Sakhuja, MSc 2012. Co-direction with Dr Patrick Laprise (directeur). 

Irfan Bukhari, PhD 2012. Co-direction with Dr Martin Simard (directeur). Now PDF at Harvard University

Karine Drapeau, MSc 2012. Tableau d'honneur de l'Université Laval.  Now Specialist II- Analytic Development at Medicago. 

Rémi Buisson, PhD 2012. Tableau d'honneur de l'Université Laval. Now PDF at Harvard. 

Ranjan Maity, PhD 2014. Now a PDF at University of Alberta. 

Jana Krietsch, PhD 2014 (co-direction with Michèle Rouleau/Guy Poirier). Scientific officer in Massimo Lopes lab. 

Joris Pauty, PhD 2014  (joris.pauty@hotmail.fr).  Now a PDF at Tokyo University. 

 

 

 

 

 

 

 

Stéphanie Bérubé, MSc 2015. Tableau d'honneur de l'Université Laval (steph.berube.8@hotmail.com

 

 

 

 

 

 

 

 

 

 

 

 

Marie-Michelle Genois, PhD 2015 (co-direction with Marc-Ouellette)Tableau d'honneur de l'Université Laval (mariemichelle78@hotmail.com). Now a PDF at Harvard University. 

 

 

 

 

 

 

 

 

 

 

Anthony Couturier, PhD 2016  (anthony.couturier.1@gmail.com). Now a PDF at Oxford University. 

Denis Velic, PhD 2016 (co-tutelle with Fabrice Fleury). Université de Nantes and Université Laval  (velic.d@gmail.com

Niraj Joshi, PhD 2016 (niraj7joshi@gmail.com). Now a PDF at Harvard University.  

 

 

Mariline Béliveau, MSc 2017 (mariline.beliveau23@gmail.com). R&D professional at GenePOC technologies. 

Émilie Dubois, PhD 2018 (emilie6.dubois@orange.fr) 

 

 

 

 

 

 

 

 

 

 

 

Mandy Ducy, PhD 2019 (ducymandy@gmail.com). Co-direction with Dr. Jacques Simard. 

 

 

 

Past post-doctoral fellows

Isabelle Brodeur (2005-2008), now administrative assistant (part time)

Julien Vignard (2007-2011). Now Chargé de Recherche 2, Toxalim UMR 1331 INRA/INP/UPS, Equipe "Génotoxicité et Signalisation", Toulouse. 

Julie Birraux (2008-2010)

Cyril Charbonnel (2011)

Hemanta Adhikary (2012-2016). PDF in Rob Bristow's lab at Princess Margaret Cancer Centre and Kyle Biggar lab in Carleton University (Ottawa).

 

Past research assistants

Marie-Christine Gauthier 2002-2004

Pierre Plante, 2007

Hélène Launay, technician 2008-2013

Kenny Dubois, 2014-2015 

Past trainees

Karine Jacquet, Master 2 training, 2009-2010, now a PDF in Dan Durocher lab in SLRI in Toronto  

Anne-Marie Doyon (2014-2016).

Maripier Hainse, MSc thesis writing  (2017 -

Yuandi Gao, MITACS trainee (summer 2017), Shandong University, China 

Franciele Busatto, PhD student april 2017- October 2017, and  Oct 2018-March 2019 from Jenifer Saffi's lab in Brazil (ELAP scholarship)

Simone Carvalho, simonedacostaesilva@gmail.com, PhD student Oct 2018-March 2019

Nadine Brahiti, nadine.brahiti91@gmail.com, MSc thesis writing  (2019 -

 

PHOTO ALBUM

Centre de Recherche du CHU de Québec (Axe Cancer) 

Centre de Recherche en Cancérologie de l'Université Laval

9, McMahon, Québec (Québec), Canada  G1R 2J6

Tel 418 525-4444 ext. 15154  |  Fax 418 691-5439

© 2014 Genome Stability and DNA double-strand break repair laboratory

Design: Véronique L’Italien