This is wonderful team work with the Zou lab in Harvard and Dellaire lab in Dalhousie. Congs to Rémi (former PhD student), Niraj, Amélie & all !!! Here are the highlights of the paper: ATR acts after DNA end resection to promote HR The CDK-to-ATR switch after resection is important for efficient HR ATR promotes the BRCA1-PALB2 interaction and PALB2 localization to DSBs ATR regulates PALB2 by driving a phosphorylation switch on S59 and S64 See: http://www.cell.com/molecular-cell/fulltext/S1097-2765(16)30845-0
