Great collaboration with the Hendzel and Poirier groups - see the publication in NCB !
Photo: Guy Poirier, Michael Hendzel, Jean-Yves Masson
The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice.
Ismail IH, Gagné JP, Genois MM, Strickfaden H, McDonald D, Xu Z, Poirier GG, Masson JY, Hendzel MJ.
Nat Cell Biol. 2015 Nov;17(11):1446-57. doi: 10.1038/ncb3259. Epub 2015 Oct 26.
PMID: 26502055
See also:
http://www.lefil.ulaval.ca/articles/proteine-cle-qui-ouvre-cadenas-37867.html
